Epitalon
Also known as: AEDG, AEDG peptide, Ala-Glu-Asp-Gly, Epithalamin analog, Epithalon, Epithalone
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Summary
Epitalon (AEDG) is a synthetic 4‑amino‑acid peptide (Ala‑Glu‑Asp‑Gly) investigated for telomere elongation, age‑related disease mitigation and neuroprotection. Not approved for medical use.
Mechanism of Action
Upregulates telomerase expression and modulates melatonin secretion, providing anti‑aging, cytoprotective and antioxidant effects.
Routes of Administration
Goals & Uses
- Oncology preventionOncologyLow
- Telomere lengtheningLongevityModerate
- NeuroprotectionNeurologyLow
- Telomere elongationCellular BiologyLow
- Circadian rhythm and sleep normalizationNeuroendocrineLow
- Anti-aging / LongevityAgingLow
- Immune modulationImmunologyLow
Contraindications
- Active malignancyOncologyHighUse caution or avoid depending on agent and context
- Pediatric usePopulationHigh
- PregnancyPopulationModeratePotential fetal risk or insufficient safety data
- BreastfeedingPopulationModeratePotential transfer into breast milk or insufficient safety data
Adverse Effects
- Injection site reactionsLocalCommon
- HeadacheNeurologicUnknownPain in the head or upper neck
- HypotensionCardiovascularRareLow blood pressure
- NauseaGastrointestinalUnknownFeeling of sickness or urge to vomit
- FatigueGeneralUncommonLow energy or tiredness
- Unknown long-term effectsGeneralUnknown
Drug Interactions
- Melatonin / Melatonin agonistsLow
- ImmunosuppressantsModeratePotential interaction with immune pathways or infection risk
- Melatonin agonistsLow
Population Constraints
- Pediatric patientsAgeAbsolute
- ElderlyAgeRelative
- Pregnant or lactating womenReproductiveAbsolute
- Elderly patientsAgeRelative
- Patients with history of cancerOncologyRelative
- ChildrenPediatricRelative
Regulatory Status
- European UnionUnapprovedNo marketing authorization; sold as a laboratory reagent.
- United StatesUnapprovedConsidered a research chemical; not FDA‑approved.
- United KingdomUnapprovedNot licensed for medicinal use.
Not approved by FDA, EMA or MHRA; marketed as a research chemical or dietary supplement in some jurisdictions with limited clinical evidence.
Evidence & Sources
No sources recorded yet.
Frequently Asked Questions
What is Epitalon?
Epitalon (AEDG) is a synthetic 4‑amino‑acid peptide (Ala‑Glu‑Asp‑Gly) investigated for telomere elongation, age‑related disease mitigation and neuroprotection. Not approved for medical use.
What is Epitalon used for?
Epitalon is educationally associated with: Oncology prevention, Telomere lengthening, Neuroprotection, Telomere elongation, Circadian rhythm and sleep normalization, Anti-aging / Longevity, Immune modulation. Educational only — not medical advice.
How is Epitalon administered?
Recorded routes of administration: Intramuscular, Intravenous, Nasal, Oral, Subcutaneous.
What are the potential side effects of Epitalon?
Reported adverse effects include: Injection site reactions, Headache, Hypotension, Nausea, Fatigue, Unknown long-term effects. This list is not exhaustive — consult a qualified clinician.
Who should avoid Epitalon?
Recorded contraindications: Active malignancy, Pediatric use, Pregnancy, Breastfeeding. Consult a qualified clinician before use.