GHRP-6

Growth Hormone SecretagogueRx: ResearchCompound: Research

Also known as: GHRP, Growth Hormone Releasing Peptide-6, SKF-110679

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Summary

Synthetic hexapeptide that stimulates growth hormone secretion by mimicking ghrelin; not approved for clinical use

Mechanism of Action

Ghrelin receptor agonist; stimulates GH release via hypothalamic-pituitary axis

Routes of Administration

Subcutaneous

Goals & Uses

muscle wasting/cachexiaMetabolicLow
Growth hormone deficiencyEndocrineModerate
performance enhancementAthleticLow

Contraindications

Active malignancyOncologyHighUse caution or avoid depending on agent and context
PregnancyPopulationHighPotential fetal risk or insufficient safety data
Diabetic retinopathyOphthalmologyModerate

Adverse Effects

HeadacheNeurologicUncommonPain in the head or upper neck
Cortisol and prolactin elevationEndocrineCommon
water retention/edemaMetabolicUncommon
Increased appetiteMetabolicCommon
Transient hypotensionCardiovascularUncommon

Drug Interactions

InsulinModerateMay increase risk of low blood sugar
GlucocorticoidsModerate
somatostatin analogsHigh

Population Constraints

Pediatric patientsAgeRelative
ElderlyAgeRelative
competitive athletesOccupationalAbsolute

Regulatory Status

European UnionUnapprovedNo marketing authorization
United StatesUnapprovedNot approved by FDA; research use only
United KingdomUnapprovedClass C controlled substance under Misuse of Drugs Act 1971 (analog provision)

Banned by WADA; not approved for human use in major jurisdictions

Evidence & Sources

No sources recorded yet.

Frequently Asked Questions

What is GHRP-6?

Synthetic hexapeptide that stimulates growth hormone secretion by mimicking ghrelin; not approved for clinical use

What is GHRP-6 used for?

GHRP-6 is educationally associated with: muscle wasting/cachexia, Growth hormone deficiency, performance enhancement. Educational only — not medical advice.

How is GHRP-6 administered?

Recorded routes of administration: Subcutaneous.

What are the potential side effects of GHRP-6?

Reported adverse effects include: Headache, Cortisol and prolactin elevation, water retention/edema, Increased appetite, Transient hypotension. This list is not exhaustive — consult a qualified clinician.

Who should avoid GHRP-6?

Recorded contraindications: Active malignancy, Pregnancy, Diabetic retinopathy. Consult a qualified clinician before use.