Beinaglutide

GLP 1 Receptor AgonistRx: PrescriptionCompound: Approved

Also known as: B-GLP-1, Bei Na Lu Tai, Beigelu, Beinaglutide, GLP-1 (7-36) amide (recombinant human), rhGLP-1

Educational Only — Not medical advice. Consult a qualified clinician before using any peptide.

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Summary

Beinaglutide is a long‑acting GLP‑1 analog used to improve glycaemic control in adults with type 2 diabetes; it is administered subcutaneously once daily.

Mechanism of Action

Activates the glucagon‑like peptide‑1 (GLP‑1) receptor, enhancing glucose‑dependent insulin secretion, suppressing glucagon release, and slowing gastric emptying.

Routes of Administration

Subcutaneous

Goals & Uses

  • Cardiovascular risk reductionCardiovascularLow
  • Weight reduction / anti-obesityMetabolicHigh
  • Weight reductionMetabolicModerate
  • Glycemic control in type 2 diabetesMetabolicHigh
  • Glycaemic controlDiabetesHigh
  • Beta-cell preservationMetabolicModerate

Contraindications

  • Personal or family history of medullary thyroid carcinomaOncologicHigh
  • Severe gastrointestinal diseaseGastrointestinalModerate
  • Multiple endocrine neoplasia syndrome type 2 (MEN2)OncologicHigh
  • Severe renal impairmentOrganModerateKidney function concerns
  • PregnancyPopulationModeratePotential fetal risk or insufficient safety data
  • Multiple endocrine neoplasia type 2OncologyHigh
  • Medullary thyroid carcinomaOncologyHigh
  • Type 1 diabetes mellitusEndocrineModerate

Adverse Effects

  • PancreatitisGastrointestinalRareInflammation of the pancreas
  • HypoglycemiaMetabolicUncommonAbnormally low blood glucose
  • Injection site reactionsLocalCommon
  • Hypoglycaemia (with sulfonylureas/insulin)MetabolicUncommon
  • NauseaGastrointestinalCommonFeeling of sickness or urge to vomit
  • VomitingGastrointestinalCommonForceful expulsion of stomach contents
  • DiarrheaGastrointestinalCommonLoose or frequent stools

Drug Interactions

  • InsulinModerateMay increase risk of low blood sugar
  • Oral medications (general)Low
  • WarfarinModerate
  • SulfonylureasModerateMay increase risk of low blood sugar

Population Constraints

  • PregnancyReproductive SafetyAbsolute
  • Pediatric patients (<18 years)AgeRelative
  • LactationReproductiveRelative
  • Elderly patients (>75 years)AgeRelative
  • Pediatric (<18 years)AgeAbsolute
  • Pregnant womenReproductiveRelative
  • Severe hepatic impairmentOrgan ImpairmentRelative

Regulatory Status

  • European UnionUnapprovedNo EMA assessment.
  • United StatesUnapprovedNot submitted for FDA approval.
  • United KingdomUnapprovedNot authorized by MHRA.

Approved in China (2020) for type 2 diabetes; not approved in the United States, European Union, or United Kingdom.

Evidence & Sources

No sources recorded yet.

Frequently Asked Questions

What is Beinaglutide?

Beinaglutide is a long‑acting GLP‑1 analog used to improve glycaemic control in adults with type 2 diabetes; it is administered subcutaneously once daily.

What is Beinaglutide used for?

Beinaglutide is educationally associated with: Cardiovascular risk reduction, Weight reduction / anti-obesity, Weight reduction, Glycemic control in type 2 diabetes, Glycaemic control, Beta-cell preservation. Educational only — not medical advice.

How is Beinaglutide administered?

Recorded routes of administration: Subcutaneous.

What are the potential side effects of Beinaglutide?

Reported adverse effects include: Pancreatitis, Hypoglycemia, Injection site reactions, Hypoglycaemia (with sulfonylureas/insulin), Nausea, Vomiting, Diarrhea. This list is not exhaustive — consult a qualified clinician.

Who should avoid Beinaglutide?

Recorded contraindications: Personal or family history of medullary thyroid carcinoma, Severe gastrointestinal disease, Multiple endocrine neoplasia syndrome type 2 (MEN2), Severe renal impairment, Pregnancy, Multiple endocrine neoplasia type 2, Medullary thyroid carcinoma, Type 1 diabetes mellitus. Consult a qualified clinician before use.

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