S-Hexylglutathione
Also known as: Hexyl-GSH, hexyl‑glutathione, S-n-Hexylglutathione, S‑hexylglutathione, γ-Glu-Cys(S-hexyl)-Gly
Source S-Hexylglutathione at Peptiology
Save 10% with code PEPTI-BOSSRABBIT-10
Tapping Shop Now & Save 10% copies your 10% off code PEPTI-BOSSRABBIT-10 to your clipboard. Paste it at the Peptiology checkout to claim the discount.
Summary
S-Hexylglutathione is a synthetic S‑alkylated derivative of the tripeptide glutathione (γ‑Glu‑Cys‑Gly). The hexyl group attached to the cysteine thiol increases lipophilicity and stability, and it is used primarily as a research reagent to study redox biology and as a potential antioxidant supplement.
Mechanism of Action
thiol-based antioxidant; scavenges reactive oxygen species and replenishes intracellular glutathione pools
Routes of Administration
Goals & Uses
- Oxidative stress reductionAntioxidantLow
- Anticancer research toolOncology / ResearchLow
- Multidrug resistance modulationOncology / ResearchLow
- Glyoxalase I inhibitionEnzyme Inhibition / Biochemical ToolHigh
- Glutathione S-transferase inhibitionEnzyme Inhibition / ResearchHigh
Contraindications
No contraindications recorded yet.
Adverse Effects
- Gastrointestinal irritationGastrointestinalUnknown
Drug Interactions
- acetaminophenLow
Population Constraints
- Pregnant animalsReproductiveRelative
Regulatory Status
- European UnionUnapprovedNo EMA approval; used solely in laboratory and biochemical research settings.
- United StatesUnapprovedNot an FDA‑approved drug; classified as a research chemical.
- United KingdomUnapprovedNo MHRA approval; research use only.
No approved clinical use in any jurisdiction. Used exclusively as a research reagent and biochemical tool compound.
Evidence & Sources
No sources recorded yet.
Frequently Asked Questions
What is S-Hexylglutathione?
S-Hexylglutathione is a synthetic S‑alkylated derivative of the tripeptide glutathione (γ‑Glu‑Cys‑Gly). The hexyl group attached to the cysteine thiol increases lipophilicity and stability, and it is used primarily as a research reagent to study redox biology and as a potential antioxidant supplement.
What is S-Hexylglutathione used for?
S-Hexylglutathione is educationally associated with: Oxidative stress reduction, Anticancer research tool, Multidrug resistance modulation, Glyoxalase I inhibition, Glutathione S-transferase inhibition. Educational only — not medical advice.
How is S-Hexylglutathione administered?
Recorded routes of administration: Intraperitoneal, Intravenous, Oral.
What are the potential side effects of S-Hexylglutathione?
Reported adverse effects include: Gastrointestinal irritation. This list is not exhaustive — consult a qualified clinician.