Selank
Also known as: Selanc, TP-7
Source Selank at Peptiology
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Summary
Synthetic peptide derived from tuftsin with anxiolytic, nootropic, and immunomodulatory properties; primarily studied in Russia with limited Western clinical validation
Mechanism of Action
Modulates expression of interleukin-6 (IL-6) and affects brain-derived neurotrophic factor (BDNF); exhibits anxiolytic and nootropic effects via interaction with enkephalin degradation and serotonin system modulation
Routes of Administration
Goals & Uses
- stress resiliencePsychiatricLow
- Anxiety reductionNeuropsychiatricModerate
- Cognitive enhancementNootropicLow
- Immune modulationImmunologyLow
Contraindications
- Severe renal impairmentOrganModerateKidney function concerns
- PregnancyPopulationHighPotential fetal risk or insufficient safety data
Adverse Effects
- Nasal irritationLocal/NasalCommon
- HeadacheNeurologicUncommonPain in the head or upper neck
- FatigueGeneralUncommonLow energy or tiredness
Drug Interactions
- BenzodiazepinesModerate
- serotonergic agentsLow
Population Constraints
- ElderlyAgeRelative
- Pediatric useAgeRelative
Regulatory Status
- European UnionUnapprovedNot EMA approved; regulatory status varies by member state
- United StatesUnapprovedNot FDA approved; sold as research chemical or unregulated supplement
- United KingdomUnapprovedNot MHRA approved; may fall under Novel Foods or medicinal product regulations depending on claims
Not approved by FDA or EMA; available as research chemical or dietary supplement in some jurisdictions; developed by Institute of Molecular Genetics, Russian Academy of Sciences
Evidence & Sources
No sources recorded yet.
Frequently Asked Questions
What is Selank?
Synthetic peptide derived from tuftsin with anxiolytic, nootropic, and immunomodulatory properties; primarily studied in Russia with limited Western clinical validation
What is Selank used for?
Selank is educationally associated with: stress resilience, Anxiety reduction, Cognitive enhancement, Immune modulation. Educational only — not medical advice.
How is Selank administered?
Recorded routes of administration: Intranasal, Subcutaneous.
What are the potential side effects of Selank?
Reported adverse effects include: Nasal irritation, Headache, Fatigue. This list is not exhaustive — consult a qualified clinician.
Who should avoid Selank?
Recorded contraindications: Severe renal impairment, Pregnancy. Consult a qualified clinician before use.